Coenzyme A

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

辅酶 A 是所有活细胞中必需的辅因子，由泛酸（维生素 B5）、三磷酸腺苷（ATP）和半胱氨酸合成。

Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.Covalent binding of Coenzyme A to Peroxiredoxin 5 (Prdx5) results in complete inhibition of its peroxidase activity, which is reversed by reduction with DTT. Many human pathologies, including cancer, diabetes, and neurodegeneration, have been associated with abnormal biosynthesis and homeostasis of CoA and its derivatives.

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Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

Cardiovascular system

Hyperlipoproteinemia

85-61-0

767.53

C21H36N7O16P3S

>98% (HPLC)

In Vitro:?H2O : 125 mg/mL (162.86 mM)

CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCS

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(-20℃)

With Ice Pack

≥ 2 years